TB-500 (Thymosin Beta-4) Research Guide

TB-500 is the synthetic active fragment of thymosin beta-4, a 43-amino-acid protein present in nearly every mammalian cell. Its research profile is built on one central mechanism: actin regulation.

Actin and cell migration

Actin is the structural protein cells use to move. Thymosin beta-4 sequesters actin monomers, regulating polymerisation — and cell migration is fundamental to how tissue-repair models progress. This makes TB-500 a staple in wound-model and cell-motility research.

What distinguishes it from BPC-157

BPC-157's literature is about signalling pathways; TB-500's is about cellular machinery. Complementary mechanisms are why the pair are so often studied together, individually or via our fixed-ratio blend vial.

Handling

Lyophilised at -20°C, reconstituted at 2-8°C, gentle swirling only. TB-500 is supplied as 5mg and 10mg vials, HPLC-verified with batch documentation available on request.

For laboratories and peptide businesses buying at volume, wholesale trade packs — sourced and tested in Australia — are available through our wholesale and white-label page.

All compounds discussed are for in-vitro laboratory research only and are not for human or veterinary use.